IntegromeDB integrates hundreds of curated and publicly contributed data sources and provides integrated view on the genomic, proteomic, transcriptomic, genetic and functional information currently available. Information featured in the database includes gene function, orthologies, gene expression, pathways and protein-protein interactions, mutations and SNPs, disease relationships, related drugs and compounds.
| Examples: | Name/Synonim | External ID | Keywords | Wildcard/AND/OR |
|
EGFR ESR1 CDC42 |
ENST00000338799 x84746 2BIP |
diabetes cancer neurodegenerative |
p53* Neurodeg* OR brain* p53* AND cancer* |
|
| Publications: | ||||
| "IntegromeDB: an integrated system and biological search engine", BMC Genomics, 2012. | ||||
| "Semantic Integration of Data on Transcriptional Regulation.", Bioinformatics, 2010. | ||||
IntegromeDB statistics
| Category | Number of entities | Examples |
|
Relations Physical interactions Small molecules Proteins Publications Interactions Genes Orthology groups Sets Biochemical reactions Run of genes Organisms Pathways Experiments Protein molecular functions Microarray experiments Cells Grouping Othe plysical entities Enzymes Classes Collections Functional categories |
197 616 248 56 882 654 9 957 879 5 647 773 3 189 964 2 750 297 2 546 676 2 143 144 2 115 885 1 715 618 372 937 334 230 150 582 45 125 8 570 5 971 1 341 1 011 831 766 47 26 25 |
Co-citation, co-expression Protein-protein, protein-DNA, ligand-protein, ... Chemical molecules, ligands, compounds, glycans p53, NF-kappaB PubMed Genetic interactions TP53 COGs Photosynthesis, respiration Operon Homo sapiens KEGG Proteomics experiments protein kinase NCBI GEO experiments Pyramidal neurons Homology clusters Regulatory regions, promoters glyoxalase I gene, protein, regulatory region Families, PFAM protein classification |